In elderly patients with diffuse large B-cell lymphoma (DLBCL),* six cycles of CHOP-14 chemotherapy** in combination with eight applications of rituximab (R-CHOP-14) is as efficacious as eight cycles of R-CHOP-14 and should be the preferred treatment for elderly patients, according to authors reporting in an Article to be published early Online and in the February issue of The Lancet Oncology.